Thalassemia is an inherited blood disorder caused when the body produces an abnormal form of haemoglobin which results in excessive destruction of red blood cells and leads to anaemia.
- TYPES OF THALASSEMIA
- SIGNS AND SYMPTOMS OF THALASSEMIA
- CAUSES OF THALASSEMIA
- PATHOPHYSIOLOGY OF THALASSEMIA
- DIAGNOSIS OF THALASSEMIA
- TREATMENTS FOR THALASSEMIA
- PROGNOSIS OF THALASSEMIA
- COMPLICATIONS OF THALASSEMIA
- THALASSEMIA AND AYURVEDA
- NIDANA- AYURVEDIC CAUSES OF THALASSEMIA
- PURVAROOPAM- AYURVEDIC PREMONITORY SYMPTOMS OF THALASSEMIA
- SAMPRAPTI – AYURVEDIC PATHOGENESIS OF THALASSEMIA
- LAKSHANA- AYURVEDIC SIGNS AND SYMPTOMS OF THALASSEMIA
- AYURVEDIC PROGNOSIS OF THALASSEMIA
- CHIKITSA- AYURVEDIC TREATMENT FOR THALASSEMIA
- AYURVEDIC LOCAL TREATMENT FOR THALASSEMIA
- AYURVEDIC SAMANA TREATMENT FOR THALASSEMIA
- AYURVEDIC SHODHANA TREATMENT FOR THALASSEMIA
- COMMONLY USED AYURVEDIC MEDICINES FOR THALASSEMIA
- HOME REMEDIES FOR THALASSEMIA
- DIET AND BEHAVIOUR FOR THALASSEMIA
- YOGA FOR THALASSEMIA
- RESEARCH PAPERS ON AYURVEDIC MANAGEMENT OF THALASSEMIA
TYPES OF THALASSEMIA
- Alpha thalassemia
- Beta thalassemia
SIGNS AND SYMPTOMS OF THALASSEMIA
- Fatigue
- Yellow discolouration in the skin
- Pallor
- Anaemia
- Shortness of breath
- Dark urine
- Slow growth
CAUSES OF THALASSEMIA
- Gene mutations
PATHOPHYSIOLOGY OF THALASSEMIA
In the case of thalassemia mutations occur in the gene that makes haemoglobin. This causes impaired production of one type of globin chain (alpha chain in alpha thalassemia and beta chain in beta-thalassemia). Unpaired chains cause problems with RBC production and maturation leads to haemolytic anaemia.
DIAGNOSIS OF THALASSEMIA
- Complete blood count
- Haemoglobin count
- Prenatal testing – chorionic villus sampling, amniocentesis
TREATMENTS FOR THALASSEMIA
- Blood transfusion
- Stem cell transplant
- Iron chelation therapy
PROGNOSIS OF THALASSEMIA
- Prognosis is based on the type and severity of thalassemia. Some people with beta-thalassemia intermedia and major can be cured with a stem cell transplant.
COMPLICATIONS OF THALASSEMIA
- Iron overload
- Spleen enlargement
- Heart problems
- Bone deformities
THALASSEMIA AND AYURVEDA
- In Ayurveda, thalassemia is considered as ‘beeja dushtajanya pandu roga’.
NIDANA- AYURVEDIC CAUSES OF THALASSEMIA
- Tridosha prakopa
- Beeja dushti
PURVAROOPAM- AYURVEDIC PREMONITORY SYMPTOMS OF THALASSEMIA
- No specific premonitory symptoms
SAMPRAPTI – AYURVEDIC PATHOGENESIS OF THALASSEMIA
- Vitiation of tridoshas along with beejadushti affects the raktavaha srothas. Rakta dhatu is affected and produces rakta vikriti. Persistent production of vikrita rakta dhatu leads to symptoms of pandu (anaemia).
LAKSHANA- AYURVEDIC SIGNS AND SYMPTOMS OF THALASSEMIA
- Haaridra netra twak – yellow discolouration of eyes, skin
- Vivarna mutratha – dark urine
- Pandu – anaemia
- Pleehodara – spleen enlargement
AYURVEDIC PROGNOSIS OF THALASSEMIA
- The symptoms are managed by adopting treatment for pandu, yakrit roga, pleeha roga and rakta sodhana (blood purification).
CHIKITSA- AYURVEDIC TREATMENT FOR THALASSEMIA
AYURVEDIC SAMANA TREATMENT FOR THALASSEMIA
- Ama pachana
- Deepana
- Srotho sodhana
- Rakta prasadana
- Shonitasthapana
AYURVEDIC SHODHANA TREATMENT FOR THALASSEMIA
- Virechana – purgation
COMMONLY USED AYURVEDIC MEDICINES FOR THALASSEMIA
Internal administration
- Avipatti churna
- Vasaguluchyadi kashayam
- Drakshadi lehyam
- Datri avaleha
- Triphaladi avaleha
- Guduchyadi kashaya
External application
- abhyanga – chandanadi tailam, arukaladi tailam
HOME REMEDIES FOR THALASSEMIA
- Avoid excess iron-containing diet
- Consume vitamin B containing diets
DIET AND BEHAVIOUR FOR THALASSEMIA
- Avoid food items that produce dosha imbalance like sour, cold and dry food, hard to digest. Because dosha imbalance aggravates the symptoms.
- Consume easily digestible food items
- Take proper rest.
YOGA FOR THALASSEMIA
- Nadi Shuddi Pranayam – refresh the body and mind
The patient needs to be seated in a meditative posture with the head and spine erect, and the body relaxed. The patient has to close one nostril (e.g. left nostril if using the right hand and vice versa) with the thumb and exhale completely through the other nostril. Again, he will have to breathe in deeply through the other nostril while the opposite nostril is still closed with the thumb.
RESEARCH PAPERS ON AYURVEDIC MANAGEMENT OF THALASSEMIA
- Ayurvedic management of Thalassemia Major-A review of clinical researches conducted at IPGT & RA, Jamnagar
https://ijam.co.in/index.php/ijam/article/download/06092015/299
2. Evaluation of Dhatri Avaleha as adjuvant therapy in Thalassemia (Anukta Vyadhi in Ayurveda)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215316/
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